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Immunogen sequence: MAGPLQGGG ARALDLLRGL PRVSLANLKP NPGSKKPERR PRGRRRGRKC GRGHKGERQR GTRPRLGFEG GQTPFYIRIP KYGFNEGHSF RRQYKPLSLN RLQYLIDLGR VDPSQPIDLT QLVNGRGVTI QPLKRDYGVQ LVEEGADTFT AKVNIEVQLA SELAIAAIEK NGGVVTTAFY DPRSLDIVCK PVPFFLRGQP IPKRMLPPEE LVPYYTDAKN RGYLADPAKF PEARLELARK YGYILPDITK DELFKMLCTR KDPRQIFFGL APGWVVNMAD KKILKPTDEN LLKYYTS (1-296 aa encoded by BC000891)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 39S ribosomal protein L15, mitochondrial; L15mt; Large ribosomal subunit protein uL15m; MRP-L15; ribosomal protein, mitochondrial, L7
Gene Aliases: HSPC145; L15mt; MRP-L15; MRP-L7; MRPL15; RPML7
UniProt ID: (Human) Q9P015, (Mouse) Q9CPR5
Entrez Gene ID: (Human) 29088, (Rat) 297799, (Mouse) 27395
Molecular Function: ribosomal protein
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