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Antibody detects endogenous levels of total MRPL16.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008].
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Protein Aliases: 39S ribosomal protein L16, mitochondrial; L16mt; Large ribosomal subunit protein uL16m; mitochondiral ribosomal protein L16; MRP-L16; rm16
Gene Aliases: 2310039D06Rik; L16mt; MRP-L16; MRPL16; PNAS-111
UniProt ID: (Human) Q9NX20, (Rat) Q5M818, (Mouse) Q99N93
Entrez Gene ID: (Human) 54948, (Rat) 293754, (Mouse) 94063
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