|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:100|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthesized peptide derived from internal of human MRPL16.|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.4, with 50% glycerol|
|Contains||0.02% sodium azide|
The antibody detects endogenous levels of total MRPL16 protein.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 39S ribosomal protein L16; 39S ribosomal protein L16, mitochondrial; L16mt; mitochondrial; Mitochondrial large ribosomal subunit protein uL16m; mitochondrial ribosomal protein L16; MRP-L16
Gene Aliases: L16mt; MRP-L16; MRPL16; PNAS-111
UniProt ID: (Human) Q9NX20
Entrez Gene ID: (Human) 54948
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