Recommended positive controls: 293T, A431, Jurkat, Raji.
Predicted reactivity: Mouse (90%), Rat (89%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 39S ribosomal protein L15, mitochondrial; 39S ribosomal protein L19, mitochondrial; L15mt; L19mt; Mitochondrial large ribosomal subunit protein bL19m
Gene Aliases: KIAA0104; L19mt; MRP-L15; MRP-L19; MRPL15; MRPL19; RLX1; RPML15
UniProt ID: (Human) P49406
Entrez Gene ID: (Human) 9801
Molecular Function: ribosomal protein