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          • Primary Antibodies ›
          • MRPL2 Antibodies

          Invitrogen

          MRPL2 Polyclonal Antibody

          View all (6) MRPL2 antibodies

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          Cite MRPL2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          MRPL2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          MRPL2 Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          MRPL2 Antibody (PA5-103522) in WB

          Western blot analysis of MRPL2 in various samples (Lane 1: 293 cells treated with the blocking peptide
          Lane 2: 293 cells
          Lane 3: rat lung tissue
          Lane 4: mouse heart tissue
          Lane 5: HeLa cells). Samples were incubated with MRPL2 polyclonal antibody (Product # PA5-103522).
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          MRPL2 Antibody in Western Blot (WB)
          MRPL2 Antibody in Western Blot (WB)
          MRPL2 Antibody in Western Blot (WB)
          MRPL2 Polyclonal Antibody

          Product Details

          PA5-103522

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:3,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthesized peptide derived from human MRPL2(Accession Q5T653), corresponding to amino acid residues A242-M292.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2852858

          Product Specific Information

          Antibody detects endogenous levels of total MRPL2.

          Target Information

          Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 39S ribosomal protein L2, mitochondrial; L2mt; Large ribosomal subunit protein uL2m; mitochondrial large ribosomal subunit protein uL2m; MRP-L2; ribosomal protein, mitochondrial, L14; unnamed protein product

          View more View less

          Gene Aliases: CGI-22; MRP-L14; MRPL2; RPML14; uL2m

          View more View less

          UniProt ID: (Human) Q5T653, (Rat) Q498T4, (Mouse) Q9D773

          View more View less

          Entrez Gene ID: (Human) 51069, (Rat) 301240, (Mouse) 27398

          View more View less

          Function(s)
          RNA binding structural constituent of ribosome poly(A) RNA binding ribosomal protein
          Process(es)
          translation mitochondrial translation
          It has to be done as per old AB suggested Products section.

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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