Immunogen sequence: ASQEHGLKYP ALIGNLVKCQ VELNRKVLAD LAIYEPKTFK SLAALASRRR HEGFAAALGD GKEPEGIFSR VVQYH
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 21q. [provided by RefSeq, Jul 2008].
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Protein Aliases: 39S ribosomal protein L20, mitochondrial; L20mt; Mitochondrial large ribosomal subunit protein bL20m
Gene Aliases: L20mt; MRP-L20; MRPL20
UniProt ID: (Human) Q9BYC9
Entrez Gene ID: (Human) 55052
Molecular Function: ribosomal protein