Immunogen sequence: ERVRVSTRSG RIIPKPEFPR ADGIVPETWI DGPKDTSVED ALERTYVPCL KTLQEEVMEA MGIKETRKYK KVYW
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E. coli counterpart. Sequence analysis identified two transcript variants that encode the same protein.
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Protein Aliases: 39S ribosomal protein L24, mitochondrial; FLJ20917; L24mt; MGC22737; MGC9831; Mitochondrial large ribosomal subunit protein uL24m; MRPL24 protein
Gene Aliases: L24mt; MRP-L18; MRP-L24; MRPL24
UniProt ID: (Human) Q96A35
Entrez Gene ID: (Human) 79590
Molecular Function: ribosomal protein