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MRPL39 Antibody (PA5-106678) in IHC (P)
Immunohistochemistry analysis of MRPL39 in mouse muscle tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with MRPL39 polyclonal antibody (Product # PA5-106678) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-106678
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MRPL39(Accession Q9NYK5), corresponding to amino acid residues L293-T338.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2854346
Product Specific Information
Antibody detects endogenous levels of total MRPL39.
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 39S ribosomal protein L39, mitochondrial; 39S ribosomal protein L5, mitochondrial; L39mt; L5mt; Large ribosomal subunit protein mL39; mitochondrial ribosomal protein L39; MRP-L39; ribosomal protein, mitochondrial, L5
Gene Aliases: C21orf8; C21orf92; L39mt; MRP-L5; MRPL39; MRPL5; MSTP003; ORF22; PRED22; PRED66; RPML5
UniProt ID: (Human) Q9NYK5, (Mouse) Q9JKF7
Entrez Gene ID: (Human) 54148, (Rat) 684304, (Mouse) 27393
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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