Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
MRPL46 Fusion Protein Ag9837 (1-279 aa encoded by BC017883) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.27 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MAAPVRRTL LGVAGGWRRF ERLWAGSLSS RSLALAAAPS SNGSPWRLLG ALCLQRPPVV SKPLTPLQEE MASLLQQIEI ERSLYSDHEL RALDENQRLA KKKADLHDEE DEQDILLAQD LEDMWEQKFL QFKLGARITE ADEKNDRTSL NRKLDRNLVL LVREKFGDQD VWILPQAEWQ PGETLRGTAE RTLATLSENN MEAKFLGNAP CGHYTFKFPQ AMRTESNLGA KVFFFKALLL TGDFSQAGNK GHHVWVTKDE LGDYLKPKYL AQVRRFVSDL (1-279 aa encoded by BC017883)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 39S ribosomal protein L46, mitochondrial; L46mt; Mitochondrial large ribosomal subunit protein mL46; MRP-L46; P2ECSL
Gene Aliases: 3110052F15Rik; C15orf4; C80107; LIECG2; MRPL46; P2ECSL
UniProt ID: (Human) Q9H2W6, (Rat) Q5RK00, (Mouse) Q9EQI8
Entrez Gene ID: (Human) 26589, (Rat) 293054, (Mouse) 67308
Molecular Function:
ribosomal protein
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