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MRPL46 Antibody (PA5-109983) in IHC (P)
Immunohistochemistry analysis of MRPL46 in paraffin-embedded human colon carcinoma. Samples were incubated with MRPL46 Polyclonal antibody (Product # PA5-109983) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-109983
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-283 of mouse Mrpl46 (NP_0758201)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.97 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855394
Product Specific Information
Immunogen sequence: MAAPVGRTLL GLARGWRQLD RFWAGSSRGL SLEAASSSSR SPWRLSGALC LQRPPLITKA LTPLQEEMAG LLQQIEVERS LYSDHELRAL DEAQRLAKKK ADLYDEEQEQ GITLAQDLED MWEQAFLQFR PGARETEADK KNDRTSLHRK LDRNLVLLVR EKLGDQDVWM LPQVEWQPGE TLRGTAERIL ATLSENNMEA KFLGNAPCGH YKFKFPKAIQ TESDLGVKVF FFKALLLTGD FVQAGKKSRH VWASKEELGD YLQPKYLAQV RRFLLDSDGL SCL
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 39S ribosomal protein L46, mitochondrial; L46mt; Large ribosomal subunit protein mL46; MRP-L46; P2ECSL
Gene Aliases: 3110052F15Rik; C15orf4; C80107; LIECG2; MRPL46; P2ECSL
UniProt ID: (Human) Q9H2W6, (Rat) Q5RK00, (Mouse) Q9EQI8
Entrez Gene ID: (Human) 26589, (Rat) 293054, (Mouse) 67308
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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