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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. This gene lies adjacent to and downstream of the gonadotropin-releasing hormone precursor gene.
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Protein Aliases: 28S ribosomal protein S13, mitochondrial; 28S ribosomal protein S26, mitochondrial; MRP-S13; MRP-S26; rt26; S13mt; S26mt; serologically defined breast cancer antigen NY-BR-87; Small ribosomal subunit protein mS26
Gene Aliases: C20orf193; dJ534B8.3; GI008; MRP-S13; MRP-S26; MRPS13; MRPS26; NY-BR-87; RPMS13
UniProt ID: (Human) Q9BYN8
Entrez Gene ID: (Human) 64949
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