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Proteintech
MRPS30 Polyclonal Antibody
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Product Details
18441-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MRPS30 Fusion Protein Ag13271 (89-439 aa encoded by BC007735)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Amount
28.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKYMVYPQT FALNADRWYQ YFTKTVFLSG LPPPPAEPEP EPEPEPEPAL DLAALRAVAC DCLLQEHFYL RRRRRVHRYE ESEVISLPFL DQLVSTLVGL LSPHNPALAA AALDYRCPVH FYWVRGEEII PRGHRRGRID DLRYQIDDKP NNQIRISKQL AEFVPLDYSV PIEIPTIKCK PDKLPLFKRQ YENHIFVGSK TADPCCYGHT QFHLLPDKLR RERLLRQNCA DQIEVVFRAN AIASLFAWTG AQAMYQGFWS EADVTRPFVS QAVITDGKYF SFFCYQLNTL ALTTQADQNN PRKNICWGTQ SKPLYETIED NDVKGFNDDV LLQIVHFLLN RPKEEKSQLL EN (89-439 aa encoded by BC007735)
Target Information
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-S30 (mitochondrial ribosomal protein S30), also known as PDCD9 (programmed cell death protein 9), is a 439 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 28S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. MRP-S30 is expressed in kidney, liver, heart and skeletal muscle. The gene encoding MRP-S30 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 28S ribosomal protein S30, mitochondrial; 39S ribosomal protein S30, mitochondrial; Large ribosomal subunit protein mL65; Large ribosomal subunit protein mS30; mitochondrial large ribosomal subunit protein mL65; mitochondrial large ribosomal subunit protein mS30; MRP S30; MRP-S30; programmed cell death 9; Programmed cell death protein 9; S30mt; unnamed protein product
Gene Aliases: 2610020A16Rik; AA968347; BM-047; mL65; MRP-S30; MRPS30; PAP; PDCD9; S30mt
UniProt ID: (Human) Q9NP92, (Mouse) Q9D0G0
Entrez Gene ID: (Human) 10884, (Mouse) 59054, (Rat) 294767
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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