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Invitrogen
MRPS30 Polyclonal Antibody
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FIGURE: 1 / 7
MRPS30 Antibody (PA5-101669) in ICC/IF
Immunofluorescent analysis of MRPS30 in 3T3 cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and MRPS30 polyclonal antibody (Product # PA5-101669) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-101669
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MRPS30(Accession Q9NP92), corresponding to amino acid residues Q382-E432.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total MRPS30.
Target Information
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and are essential for protein synthesis within mitochondria. MRP-S30 (mitochondrial ribosomal protein S30), also known as PDCD9 (programmed cell death protein 9), is a 439 amino acid protein that localizes to the mitochondrion, where it exists as a component of the 28S ribosomal subunit and works in conjunction with other MRPs to mediate protein synthesis. MRP-S30 is expressed in kidney, liver, heart and skeletal muscle. The gene encoding MRP-S30 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 28S ribosomal protein S30, mitochondrial; 39S ribosomal protein S30, mitochondrial; Large ribosomal subunit protein mL65; Large ribosomal subunit protein mS30; MRP S30; MRP-S30; programmed cell death 9; Programmed cell death protein 9; S30mt
Gene Aliases: 2610020A16Rik; AA968347; BM-047; MRP-S30; MRPS30; PAP; PDCD9; S30mt
UniProt ID: (Human) Q9NP92, (Mouse) Q9D0G0
Entrez Gene ID: (Human) 10884, (Mouse) 59054
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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