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Product Details
16288-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2400 | View 1 publication 1 publication |
Immunocytochemistry (ICC/IF) |
1:10-1:100 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
MRPS31 Fusion Protein Ag9434 (63-395 aa encoded by BC022045) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.31 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: NSVICSKKD KQSVRTEEIS KETSESQDSE KENTKKDLLG IIKGMKVELS TVNVRTTKPP KRRPLKSLEA ALGRLRRATE YAPKKRIEPL SPELVAAASA VADSLPFDKQ TTKSELLSQL QQHEEESRAQ RDAKRPKISF SNIISDMKVA RSATARVRSR PELRIQFDEG YDNYPGQEKT DDLKKRKNIF TGKRLNIFDM MAVTKEAPET DTSPSLWDVE FAKQLATVNE QPLQNGFEEL IQWTKEGKLW EFPINNEAGF DDDGSEFHEH IFLEKHLESF PKQGPIRHFM ELVTCGLSKN PYLSVKQKVE HIEWFRNYFN EKKDILKESN IQFN (63-395 aa encoded by BC022045)
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 28S ribosomal protein S31, mitochondrial; Imogen 38; islet mitochondrial antigen, 38 kD; Mitochondrial small ribosomal subunit protein mS31; MRP-S31; S31mt
Gene Aliases: 1500002D03Rik; AA960481; Imogen38; Imogen44; IMOGN38; MRP-S31; MRPS31; S31mt
UniProt ID: (Human) Q92665, (Rat) B0BN56, (Mouse) Q61733
Entrez Gene ID: (Human) 10240, (Rat) 290850, (Mouse) 57312
Molecular Function:
ribosomal protein
translational protein
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