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Product Details
PA5-109985
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 66-395 of human MRPS31 (NP_005821.2).
Conjugate
Unconjugated
Form
Liquid
Concentration
0.60 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855396
Product Specific Information
Immunogen sequence: ICSKKDKQSV RTEETSKETS ESQDSEKENT KKDLLGIIKG MKVELSTVNV RTTKPPKRRP LKSLEATLGR LRRATEYAPK KRIEPLSPEL VAAASAVADS LPFDKQTTKS ELLSQLQQHE EESRAQRDAK RPKISFSNII SDMKVARSAT ARVRSRPELR IQFDEGYDNY PGQEKTDDLK KRKNIFTGKR LNIFDMMAVT KEAPETDTSP SLWDVEFAKQ LATVNEQPLQ NGFEELIQWT KEGKLWEFPI NNEAGFDDDG SEFHEHIFLE KHLESFPKQG PIRHFMELVT CGLSKNPYLS VKQKVEHIEW FRNYFNEKKD ILKESNIQFN
Target Information
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 28S ribosomal protein S31, mitochondrial; Imogen 38; MRP-S31; Small ribosomal subunit protein mS31
Gene Aliases: IMOGN38; MRP-S31; MRPS31; S31mt
UniProt ID: (Human) Q92665, (Rat) B0BN56
Entrez Gene ID: (Human) 10240, (Rat) 290850
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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