Peptide sequence: TGSLSIISGK QSTKPFDLSS LTSNAVSSVT AGAGLFLLAD SMVALRTASQ
Sequence homology: Dog: 79%; Human: 100%
This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
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Protein Aliases: CD20 antigen-like 4; CD20/FC-epsilon-RI-beta family member 4; Four-span transmembrane protein 2; high affinity immunoglobulin epsilon receptor beta subunit; Membrane-spanning 4-domains subfamily A member 7; membrane-spanning 4-domains, subfamily A, member 7; MGC22368
Gene Aliases: 4SPAN2; CD20L4; CFFM4; MS4A7; MS4A8
UniProt ID: (Human) Q9GZW8
Molecular Function: receptor