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          • Primary Antibodies ›
          • Septin-9 Antibodies

          Fabgennix

          MSF Polyclonal Antibody, Biotin

          View all (22) Septin-9 antibodies

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          Cite MSF Polyclonal Antibody, Biotin

          Additional Information:
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          MSF Polyclonal Antibody, Biotin

          Product Details

          SEPT9-BIOTIN

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          -

          ELISA (ELISA)

          1:10,000
          -

          Immunoprecipitation (IP)

          1:50-1:250
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide taken within amino acid region 1-60 on SEPT9 protein.
          3D Epitope / Immunogen

          Conjugate

          Biotin Biotin Biotin

          Form

          Liquid

          Concentration

          0.5-1.5 mg/mL

          Purification

          Affinity chromatography

          Storage buffer

          proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucinezipper motifs, which allow homodimerization as well as heterodimerization with a variety of other bZip transcription factors. Large Mafs also contain an acidic transactivation domain absent in the small Maf proteins. Although they do not possess inherent transactivation activity, small Maf proteins can act as positive regulators of transcription by targeting transcriptionally active dimerization partners to specific DNA regulatory elements. Conversely, small Mafs can act also as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can replace active dimers. Human MafF was isolated in a yeast one-hybrid system from a human myometrium cDNA library. Human MAFF encodes a 164 amino acids proten. Like other small MAFF proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain. The three small Maf proteins have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response. Interestingly, these three proteins regulate the stress response via different mechanisms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: E-septin; Eighth septin; Eseptin; MLL septin-like fusion; MLL septin-like fusion protein; MLL septin-like fusion protein MSF-A; Ov/Br septin; Ovarian/Breast septin; peanut-like 4; Septin D1; Septin-9; Septin-like protein; SL3-3 integration site 1 protein; SLP; unnamed protein product

          View more View less

          Gene Aliases: AF17q25; Eseptin; KIAA0991; MSF; MSF1; NAPB; PNUTL4; SEPT9; SeptD1; SEPTIN9; SINT1; Slpa

          View more View less

          UniProt ID: (Human) Q9UHD8, (Rat) Q9QZR6, (Mouse) Q80UG5

          View more View less

          Entrez Gene ID: (Human) 10801, (Rat) 83788, (Mouse) 53860

          View more View less

          Function(s)
          nucleotide binding GTPase activity protein binding GTP binding cadherin binding binding, bridging molecular_function cytoskeletal protein
          Process(es)
          protein localization actin cytoskeleton organization septin cytoskeleton organization cell division cytoskeleton-dependent cytokinesis positive regulation of nonmotile primary cilium assembly biological_process protein heterooligomerization cell cycle
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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