Invitrogen

MSH4 Polyclonal Antibody

View all (11) MSH4 antibodies

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MSH4 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of MSH4 in Hela cells using a MSH4 polyclonal antibody (Product # PA5-97982) at a dilution of 1:100. Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L) secondary antibody was used.

MSH4 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemical analysis of MSH4 in paraffin embedded human testis tissue using a MSH4 polyclonal antibody (Product # PA5-97982) at a dilution of 1:100.

MSH4 Antibody in Western Blot (WB) — Western Blot analysis of MSH4 using a MSH4 Polyclonal antibody (Product # PA5-97982) at a concentration of 3 µg/mL. Positive WB detected in: Mouse lung tissue, Mouse kidney tissue, Human placenta tissue. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 105 kDa.

Product Details

PA5-97982

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:5,000	-
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	1:50-1:200	-
ELISA (ELISA)	Assay-Dependent	-

Product Specifications
Species Reactivity	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Recombinant Human MutS protein homolog 4 protein (501-800AA) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	3 mg/mL
Purification	Protein G
Storage buffer	PBS, pH 7.4, with 50% glycerol
Contains	0.03% ProClin 300
Storage conditions	-20°C or -80°C if preferred
RRID	AB_2812596

Target Information

MSH4 is involved in meiotic recombination. MSH4 is also required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: hMSH4; mMsh4; MutS homolog 4 variant iota 1; MutS homolog 4 variant theta 1; MutS protein homolog 4

Gene Aliases: 4930485C04Rik; AV144863; mMsh4; MSH4

UniProt ID: (Human) O15457, (Mouse) Q99MT2

Entrez Gene ID: (Human) 4438, (Mouse) 55993

Molecular Function: DNA metabolism protein

meiotic mismatch repair ovarian follicle development mismatch repair synapsis reciprocal meiotic recombination spermatogenesis female gamete generation meiotic nuclear division homologous chromosome segregation chiasma assembly meiotic cell cycle

Process(es)

DNA binding damaged DNA binding protein binding ATP binding mismatched DNA binding nucleotide binding DNA-dependent ATPase activity