The DNA mismatch repair MSH2/MSH6 heterodimer is responsible for the detection of DNA damage, and may promote apoptosis in normal cells, thus protecting mammals from ultraviolet-induced malignant transformation and hence the prevention of skin cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA mismatch repair protein Msh6; G/T mismatch-binding protein; GTBP; hMSH6; mutS homolog 6; MutS protein homolog 6; MutS-alpha 160 kDa subunit; p160; rCG61559-like; sperm-associated protein
Gene Aliases: AU044881; AW550279; GTBP; GTMBP; HNPCC5; HSAP; MSH6; p160