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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to amino acids 150-200 of human MST1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Immunohistochemistry (Paraffin) (IHC (P))||1:50-1:200|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects endogenous protein at a molecular weight of 56 kDa.
Purity is >95% by SDS-PAGE.
The mammalian Ste20-like kinases (MST kinases), also known as Krs proteins, are members of the GCK subfamily. Ksr-1 (MST-2) and Ksr-2 (MST-1) are both direct substrates of caspase-3 that accelerate caspase-3 activation. MST-3 is ubiquitously expressed in mammalian tissue and can phosphorylate exogenous substrates as well as itself. MST-4 is highly expressed in placenta, thymus, and peripheral blood leukocytes, and it specifically activates ERK.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
KB-1458E12.1; kinase responsive to stress 2; KRS1; KRS2; mammalian STE20-like protein kinase 1; mammalian STE20-like protein kinase 2; mammalian sterile 20-like 1; MST-1; MST-2; MST1; MST1/C STK4; MST2; MST2/C; protein kinase homolog; serine/threonine kinase 3 (STE20 homolog, yeast); serine/threonine kinase 3 (Ste20, yeast homolog); serine/threonine-protein kinase 3; serine/threonine-protein kinase 4; serine/threonine-protein kinase Krs-1; serine/threonine-protein kinase Krs-2; STE20-like kinase MST1; STE20-like kinase MST2; sterile 20-like kinase 1; STK3; Yeast Sps1/Ste20-related kinase 3
0610042I06Rik; AI447339; AU020804; Kas-2; KRS1; KRS2; Mess1; MST; MST1; MST2; Mst3; Ste20; STK3; STK4; YSK3