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Fabgennix
MST3 Polyclonal Antibody
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Product Details
MST3-101AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide taken within amino acid region 460-517 on human Mammalian STE20-like protein kinase 3 / STE20-like kinase MST3 / STK24.
Conjugate
Form
Liquid
Concentration
0.5-1.5 mg/mL
Purification
Affinity chromatography
Storage buffer
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
STK24 (MST3) is a serine/threonine kinase that is a member of the GCK subfamily of STE20-like proteins. The yeast 'Sterile 20' gene (STE20) functions upstream of the mitogen-activated protein kinase (MAPK) cascade. In mammals, protein kinases related to STE20 can be divided into 2 subfamilies based on their structure and regulation. Members of the PAK subfamily (see PAK3; MIM 300142) contain a C-terminal catalytic domain and an N-terminal regulatory domain that has a CDC42 (MIM 116952)-binding domain. In contrast, members of the GCK subfamily (see MAP4K2; MIM 603166), also called the Sps1 subfamily, have an N-terminal catalytic domain and a C-terminal regulatory domain without a CDC42-binding domain. STK24 belongs to the GCK subfamily of STE20-like kinases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis secretory protein Li 95; Mammalian STE20-like protein kinase 3; mammalian sterile twenty 3 kinase; MST-3; OTTHUMP00000018594; RP11-111L24.5; serine/threonine kinase 24 (STE20 homolog, yeast); Serine/threonine-protein kinase 24; STE20-like kinase 3; STE20-like kinase MST3; sterile 20-like kinase 3
Gene Aliases: 1810013H02Rik; C76483; HEL-S-95; MST-3; MST3; MST3B; RGD1561742; STE20; STK24; STK3
UniProt ID: (Human) Q9Y6E0, (Mouse) Q99KH8, (Rat) B0LT89
Entrez Gene ID: (Human) 8428, (Mouse) 223255, (Rat) 361092
protein kinase activity
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
protein binding
ATP binding
metal ion binding
cadherin binding involved in cell-cell adhesion
nucleotide binding
kinase activity
transferase activity
transferase activity, transferring phosphorus-containing groups
molecular_function
mitotic cell cycle
protein phosphorylation
cellular component disassembly involved in execution phase of apoptosis
signal transduction
intrinsic apoptotic signaling pathway in response to oxidative stress
signal transduction by protein phosphorylation
negative regulation of cell migration
response to hydrogen peroxide
protein autophosphorylation
regulation of axon regeneration
execution phase of apoptosis
cell-cell adhesion
apoptotic process
regulation of mitotic cell cycle
phosphorylation
stress-activated protein kinase signaling cascade
activation of protein kinase activity
regulation of apoptotic process
positive regulation of axon regeneration
intracellular signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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