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Invitrogen
MST4 Polyclonal Antibody
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Product Details
PA5-22318
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human MST4. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.78 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji.
Predicted reactivity: Human (99%), Mouse (95%), Rat (97%), Zebrafish (84%), Xenopus laevis (86%), Pig (98%), Rhesus Monkey (99%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
MST4 is member of the Ste20-like kinase family of serine/threonine kinases and is overexpressed during prostate cancer development. The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Mammalian STE20-like protein kinase 4; mammalian sterile 20-like 4; MST-4; MST3 and SOK1-related kinase; OTTHUMP00000215132; OTTHUMP00000215134; RP6-213H19.1; serine/threonine protein kinase MST4; Serine/threonine-protein kinase 26; Serine/threonine-protein kinase MASK; serine/threonine-protein kinase MST4; STE20-like kinase 4; STE20-like kinase MST4
Gene Aliases: MASK; MST4; RGD1563568; STK26
UniProt ID: (Human) Q9P289
Entrez Gene ID: (Human) 51765, (Rat) 317589
mitotic cell cycle
protein phosphorylation
cellular component disassembly involved in execution phase of apoptosis
signal transduction by protein phosphorylation
microvillus assembly
response to hydrogen peroxide
regulation of apoptotic process
regulation of cell differentiation
protein autophosphorylation
regulation of hydrogen peroxide-induced cell death
apoptotic process
intracellular signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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