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Bethyl Laboratories
MST4/MASK Polyclonal Antibody
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FIGURE: 1 / 1
MST4/MASK Antibody (A300-565A) in IP
Detection of human MST4(MASK) by western blot after immunoprecipitation. Samples: Whole cell lysate (1 mg for IP; 1/4 of IP reaction loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-MST4(MASK) antibody BL2703 (Product # A300-565A) used at 3 µg/mg lysate for IP. Immunoprecipitated MST4(MASK) was blotted using rabbit anti-MST4(MASK) antibody BL2704 (Product #A300-566A), which binds a downstream epitope, at 0.1 µg/mL. Detection: Chemiluminescence with an exposure time of 3 minutes.
Product Details
A300-565A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residues 300 and 350 of human Mammalian Ste20-like Kinase 4 (Mst3 and SOK1-related kinase).
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
tris citrate/phosphate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
MST4 is member of the Ste20-like kinase family of serine/threonine kinases and is overexpressed during prostate cancer development. The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Mammalian STE20-like protein kinase 4; mammalian sterile 20-like 4; MST-4; MST3 and SOK1-related kinase; OTTHUMP00000215132; OTTHUMP00000215134; RP6-213H19.1; serine/threonine protein kinase MST4; Serine/threonine-protein kinase 26; Serine/threonine-protein kinase MASK; STE20-like kinase 4; STE20-like kinase MST4
Gene Aliases: MASK; MST4; STK26
UniProt ID: (Human) Q9P289
Entrez Gene ID: (Human) 51765
mitotic cell cycle
protein phosphorylation
cellular component disassembly involved in execution phase of apoptosis
signal transduction by protein phosphorylation
microvillus assembly
response to hydrogen peroxide
regulation of apoptotic process
regulation of cell differentiation
protein autophosphorylation
regulation of hydrogen peroxide-induced cell death
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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