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Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
MSX1 (AAH67353.1, 1 a.a. approximately 297 a.a) full-length human protein. |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
See Label |
Purification |
Affinity chromatography |
Storage buffer |
PBS, pH 7.4 |
Contains |
no preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
Sequence of this protein is as follows: MTSLPLGVKV EDSAFGKPAG GGAGQAPSAA AATAAAMGAD EEGAKPKVSP SLLPFSVEAL MADHRKPGAK ESALAPSEGV QAAGGSAQPL GVPPGSLGAP DAPSSPRPLG HFSVGGLLKL PEDALVKAES PEKPERTPWM QSPRFSPPPA RRLSPPACTL RKHKTNRKPR TPFTTAQLLA LERKFRQKQY LSIAERAEFS SSLSLTETQV KIWFQNRRAK AKRLQEAELE KLKMAAKPML PPAAFGLSFP LGGPAAVAAA AGASLYGASG PFQRAALPVA PVGLYTAHVG YSMYHLT
MSX1 is a member of the muscle segment homeobox gene family. It functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. MSX1 may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in the gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: homeobox 7; Homeobox protein Hox-7; Homeobox protein MSX-1; msh homeo box 1; Msh homeobox 1-like protein; msh homeobox homolog 1
Gene Aliases: ECTD3; HOX7; HYD1; MSX1; STHAG1
UniProt ID: (Human) P28360
Entrez Gene ID: (Human) 4487
Molecular Function:
homeodomain transcription factor
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