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Product Details
PA5-103627
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MT-ATP8(Accession P03928), corresponding to amino acid residues P15-P65.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2815991
Product Specific Information
Antibody detects endogenous levels of total MT-ATP8.
Target Information
Mitochondrial ATP synthase is composed of two multi-subunit complexes that utilize an inner membrane electrochemical gradient to catalyze the synthesis of ATP during oxidative phosphorylation. The two multi-subunit complexes are designated F1 and F0, the former of which comprises the soluble catalytic core and the latter of which comprises the membrane-spanning proton channel of ATP synthase. ATP8, also known as MT-ATP8, ATPASE8 or MTATP8, is a 68 amino acid single-pass membrane protein that localizes to mitochondria and functions as a minor subunit of the F0 complex. The gene encoding ATP8 maps to the mitochondrial chromosome and may be involved in the pathogenesis of multiple sclerosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: A6L; ATP synthase protein 8; F-ATPase subunit 8
Gene Aliases: ATP8; ATPASE8; MT-ATP8; MTATP8
UniProt ID: (Human) P03928
Entrez Gene ID: (Human) 4509
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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