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Invitrogen
MT2A Polyclonal Antibody
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FIGURE: 1 / 4
MT2A Antibody (PA5-76652) in IHC (P)
Immunohistochemistry analysis of MT2A in paraffin-embedded human liver cancer. Samples were incubated with MT2A polyclonal antibody (Product # PA5-76652) using a dilution of 1:150. Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
Product Details
PA5-76652
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Bison,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant full length Human MT2A.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
Metallothionein (MT) is a sulfhydryl- and cysteine-rich protein found in microorganisms, plants and all invertebrate and vertebrate animals. Metallothioneins are a group of ubiquitous low-molecular-weight proteins that have functional roles in cell growth, repair and differentiation. They are implicated primarily in metal ion detoxification, in that they are essential for the protection of cells against the toxicity of cadmium, mercury and copper. Metallothionein, as an acute phase or stress-response protein and free radical scavenger, is related to inflammation and cellular protection from reactive forms of oxygen, ionizing radiation, pharmacological agents and mutagens. Metallothioneins are known to be broadly expressed in heart, liver, kidney, breast and testis tissue.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Metallothionein; Metallothionein 2; metallothionein 2A; metallothionein old gene name 'MT2'; Metallothionein-2; Metallothionein-2A; Metallothionein-II; MT-2; MT-II; unnamed protein product
Gene Aliases: CES1; MT-2; MT-II; MT2; MT2A
UniProt ID: (Human) P02795, (Rat) P04355
Entrez Gene ID: (Human) 4502, (Rat) 689415
cellular copper ion homeostasis
cellular zinc ion homeostasis
detoxification of copper ion
cellular response to interleukin-3
cellular response to erythropoietin
negative regulation of growth
cellular response to cadmium ion
cellular response to copper ion
cellular response to zinc ion
nitric oxide mediated signal transduction
cellular response to drug
astrocyte activation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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