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Proteintech
MTA3 Polyclonal Antibody
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Product Details
14682-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MTA3 Fusion Protein Ag6400 (1-343 aa encoded by BC053631)
Conjugate
Form
Liquid
Concentration
0.26 mg/mL
Amount
39 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAANMYRVG DYVYFENSSS NPYLIRRIEE LNKTASGNVE AKVVCFYRRR DISNTLIMLA DKHAKEIEEE SETTVEADLT DKQKHQLKHR ELFLSRQYES LPATHIRGKC SVALLNETES VLSYLDKEDT FFYSLVYDPS LKTLLADKGE IRVGPRYQAD IPEMLLEGES DEREQSKLEV KVWDPNSPLT DRQIDQFLVV ARAVGTFARA LDCSSSVRQP SLHMSAAAAS RDITLFHAMD TLYRHSYDLS SAISVLVPLG GPVLCRDEME EWSASEASLF EEALEKYGKD FNDIRQDFLP WKSLTSIIEY YYMWKTTDRY VQQKRLKAAE AESKLKQVYI PTYS (1-343 aa encoded by BC053631)
Target Information
Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: metastasis associated 3; metastasis associated gene family, member 3; Metastasis-associated protein MTA3; unnamed protein product
Gene Aliases: 1110002J22Rik; KIAA1266; mKIAA1266; MTA3
UniProt ID: (Human) Q9BTC8, (Mouse) Q924K8
Entrez Gene ID: (Human) 57504, (Mouse) 116871, (Rat) 100362346
DNA binding
chromatin binding
transcription coactivator activity
transcription corepressor activity
protein binding
zinc ion binding
histone deacetylase binding
sequence-specific DNA binding
macromolecular complex binding
metal ion binding
transcription factor activity, sequence-specific DNA binding
molecular_function
homeodomain transcription factor
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
chromatin remodeling
regulation of transcription, DNA-templated
cell proliferation
positive regulation of G2/M transition of mitotic cell cycle
regulation of cell fate specification
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of granulosa cell proliferation
granulosa cell proliferation
regulation of stem cell differentiation
positive regulation of cell proliferation
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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