Proteintech

MTCH2 Polyclonal Antibody

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MTCH2 Antibody in Immunocytochemistry (ICC/IF) — Immunofluorescent analysis of NIH/3T3 cells using 16888-1-AP (MTCH2 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).

MTCH2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human liver using 16888-1-AP (MTCH2 antibody) at dilution of 1:100 (under 40x lens).

MTCH2 Antibody in Western Blot (WB) — Mouse liver tissue were subjected to SDS PAGE followed by western blot with 16888-1-AP (MTCH2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

MTCH2 Antibody in Immunoprecipitation (IP) — IP result of anti-MTCH2 (IP:16888-1-AP, 3ug; Detection:16888-1-AP 1:1000) with HepG2 cells lysate 4000ug.

Product Details

16888-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:3,000	View 3 publications 3 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	1:10-1:100	-
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human, Mouse
Published species	Human, Mouse, Pig
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	MTCH2 Fusion Protein Ag10399 (31-178 aa encoded by BC000875) View antigen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.24 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: GYEPLPPTI GRNIFGRQVC QLPGLFSYAQ HIASIDGRRG LFTGLTPRLC SGVLGTVVHG KVLQHYQESD KGEELGPGNV QKEVSSSFDH VIKETTREMI ARSAATLITH PFHVITLRSM VQFIGRESKY CGLCDSIITI YREEGILGF (31-178 aa encoded by BC000875)

Target Information

MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway. Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.