Invitrogen

MTERFD2 Polyclonal Antibody

View all (3) MTERFD2 antibodies

Datasheet

Protocols

Questions & Answers

Tech Support

Datasheet

Protocols

Questions & Answers

Tech Support

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MTERFD2 Antibody in Immunocytochemistry (ICC/IF) — Immunocytochemichal analysis of MTERFD2 in HepG2 cells using a Polyclonal antibody (Product # PA5-113083) at a dilution of 1:100. An Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L) secondary antibdoy was used.

MTERFD2 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunocytochemical analysis of paraffin-embeded MTERFD2 in human skeletal muscle tissue using a MTERFD2 Polyclonal antibody (Product # PA5-113083) at a dilution of 1:100.

MTERFD2 Antibody in Western Blot (WB) — Western Blot analysis of MTERFD2 in multiple sample types using a MTERFD2 polyclonal antibody (Product # PA5-113083) at a concentration of 2 µg/ml. A goat anti rabbit polyclonal secondary antibody was used at a dilution of 1:10,000. Sample types that were tested include: Lane 1: Mouse kidney tissue, Lane 2: HL60 whole cell lysate, Lane 3: A549 whole cell lysate.

Product Details

PA5-113083

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:5,000

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:50-1:200

ELISA (ELISA)

Assay-dependent

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human Transcription termination factor 4, mitochondrial protein (45-87AA)

View immunogen

Conjugate

Unconjugated

Form

Liquid

Concentration

3.5 mg/mL

Purification

Protein G

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.03% ProClin 300

Storage conditions

-20°C or -80°C if preferred

RRID

AB_2867817

Target Information

Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD2 is targeted to the mitochondria and is ubiquitously expressed, with highest expression levels in fore- and midbrain, diencephalon, spinal cord, tongue, lung liver and kidney. MTERFD2 has been suggested to play a role in organ differentiation during embryogenesis. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Mitochondrial transcription termination factor 4; MTERF domain containing 2; mTERF domain-containing protein 2; mTERF domain-containing protein 2 processed; Transcription termination factor 4, mitochondrial

Gene Aliases: 1810059A23Rik; 4933412H03Rik; HSPC096; MTERF4; MTERFD2

UniProt ID: (Human) Q7Z6M4, (Mouse) Q8BVN4

Entrez Gene ID: (Human) 130916, (Mouse) 69821

Function(s)

regulation of transcription, DNA-templated rRNA processing transcription from mitochondrial promoter protein targeting to mitochondrion heart development ribosome assembly camera-type eye development

Process(es)

double-stranded DNA binding protein binding rRNA binding RNA binding