A suggested positive control is human small intestine tissue lysate.
PA5-34531 can be used with blocking peptide PEP-1574.
Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD2 is targeted to the mitochondria and is ubiquitously expressed, with highest expression levels in fore- and midbrain, diencephalon, spinal cord, tongue, lung liver and kidney. MTERFD2 has been suggested to play a role in organ differentiation during embryogenesis. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.
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Protein Aliases: Mitochondrial transcription termination factor 4; MTERF domain containing 2; mTERF domain-containing protein 2; mTERF domain-containing protein 2 processed; Transcription termination factor 4, mitochondrial
Gene Aliases: 1810059A23Rik; 4933412H03Rik; HSPC096; MTERF4; MTERFD2