The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
MTF-2 (metal response element binding transcription factor 2), also known as PCL2 (polycomb-like protein 2) or metal-response element DNA-binding protein M96, is a 593 amino acid nuclear protein that binds the metal-regulatingelement (MRE) of the gene promoter for Metallothionein 1A. Containing two PHD-type zinc fingers, MTF-2 exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 1p22.1. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of diseaseassociated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hPCl2; Metal regulatory transcription factor 2; metal response element DNA-binding protein M96; metal response element-binding transcription factor 2; Metal-response element DNA-binding protein M96; Metal-response element-binding transcription factor 2; mPCl2; MTF2; PCL2; polycomb-like 2; Polycomb-like protein 2; putative DNA binding protein; tudor domain containing 19A; Zinc-regulated factor 1; ZiRF1
Gene Aliases: 9230112N11Rik; AA537621; C76717; dJ976O13.2; M96; MTF2; PCL2; RGD1304727; TDRD19A
Molecular Function: nucleic acid binding