This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: HFGGLIEEDD VILLAAALRI QNMVSSGRRW LREQQHRRWR LHCLKLQPLS PVPSDIEISR GQTPKAVDVL AKEIGLLADE IEIYGKSKAK V
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 88%.
One-carbon substituted forms of tetrahydrofolate (THF) are involved in the de novo synthesis of purines and thymidylate and support cellular methylation reactions through the regeneration of methionine from homocysteine. MTHFD1L is an enzyme involved in THF synthesis in mitochondria (Christensen et al., 2005 [PubMed 15611115]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 10-formyl-THF synthetase; dJ292B18.2; Formyltetrahydrofolate synthetase; formyltetrahydrofolate synthetase domain containing 1; FTHFSDC1; mitochondrial; monofunctional C1-tetrahydrofolate synthase; Monofunctional C1-tetrahydrofolate synthase, mitochondrial; MTC1THFS
Gene Aliases: dJ292B18.2; FTHFSDC1; MTC1THFS; MTHFD1L
UniProt ID: (Human) Q6UB35
Entrez Gene ID: (Human) 25902
Molecular Function: ligase