FIGURE: 1 / 1
Recommended positive controls: 293T.
Predicted reactivity: Mouse (89%), Zebrafish (80%), Xenopus laevis (81%), Chicken (85%), Bovine (89%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 5,10-methylenetetrahydrofolate reductase (NADPH); Methylenetetrahydrofolate reductase; RP11-56N19.4
Gene Aliases: MTHFR
UniProt ID: (Human) P42898
Entrez Gene ID: (Human) 4524
Molecular Function: reductase