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Product Details
PA5-56961
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MTMR3. Recombinant protein control fragment (Product #RP-95357).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2644277
Product Specific Information
Immunogen sequence: MEPSPSETSL VERPQVGSVV HRTSLGSTLS LTRSPCALPL AECKEGLVCN GAPETENRAS EQPPGLSTLQ MYPTPNGHCA NGEAGRSKDS LSR
Highest antigen sequence identity to the following orthologs: Mouse - 68%, Rat - 66%.
Target Information
This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-bisphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FYVE (Fab1 YGLO23 Vsp27 EEA1 domain) dual-specificity protein phosphatase; FYVE domain-containing dual specificity protein phosphatase 1; FYVE-DSP1; Myotubularin-related protein 3; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase; Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR3; Phosphatidylinositol-3-phosphate phosphatase; Zinc finger FYVE domain-containing protein 10; zinc finger, FYVE domain containing 10
Gene Aliases: FYVE-DSP1; KIAA0371; MTMR3; ZFYVE10
UniProt ID: (Human) Q13615
Entrez Gene ID: (Human) 8897
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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