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MTMR4 Antibody (PA5-116250) in WB
Western Blot analysis of MTMR4 using the MTMR4 Polyclonal Antibody (Product # PA5-116250) at a 1:1000 dilution. Human brain lysates were loaded at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10,000 dilution. Predicted band size: 133 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
Product Details
PA5-116250
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 695-723 amino acids from the Central region of human MTMR4
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2900884
Target Information
MTMR, a member of the myotubularin family, encodes an intracellular protein of 1, 195 amino acids, and shares approximately 47% sequence identity with MTMR3, spiking to over 70% identity in the catalytic domain and the double zinc finger (FYVE) motif. PCR analysis detects expression of MTMR4 in all human tissues examined except lung, small intestine, stomach, salivary gland, adrenal gland, and uterus. Subcellular localization of MTMR4 in transfected HeLa cells showed a perinuclear distribution, similar to that seen with MTMR3. MTMR4 dephosphorylates para-nitrophenylphosphate and phosphatidylinositol 3-phosphate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp781E194; FYVE domain-containing dual specificity protein phosphatase 2; FYVE-DSP2; MGC163449; MGC163451; MTMR7; Myotubularin-related protein 4; Zinc finger FYVE domain-containing protein 11; zinc finger, FYVE domain containing 11
Gene Aliases: FYVE-DSP2; KIAA0647; MTMR4; ZFYVE11
UniProt ID: (Human) Q9NYA4
Entrez Gene ID: (Human) 9110
protein dephosphorylation
phosphatidylinositol biosynthetic process
transforming growth factor beta receptor signaling pathway
response to denervation involved in regulation of muscle adaptation
negative regulation of transforming growth factor beta receptor signaling pathway
peptidyl-tyrosine dephosphorylation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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