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Proteintech

MTMR7 Polyclonal Antibody

View all (5) MTMR7 antibodies
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Product Details

25990-1-AP

Applications Tested Dilution Publications

Western Blot (WB)

 1:500-1:1,000 -
Product Specifications

Species Reactivity

 Human, Mouse, Rat

Host/Isotype

 Rabbit / IgG

Class

 Polyclonal

Type

 Antibody

Immunogen

MTMR7 Fusion Protein Ag23170 (514-660 aa encoded by BC130577)
View antigen

Conjugate

 Unconjugated

Form

 Liquid

Concentration

 0.3 mg/mL

Purification

 Antigen affinity chromatography

Storage buffer

 PBS, pH 7.3, with 50% glycerol

Contains

 0.1% sodium azide

Storage conditions

 -20°C

Product Specific Information

Immunogen sequence: RQSVTDYLM AVKEETQQLE EELEALEERL EKIQKVQLNC TKVKSKQSEP SKHSGFSTSD NSIANTPQDY SGNMKSFPSR SPSQGDEDSA LILTQDNLKS SDPDLSANSD QESGVEDLSC RSPSGGEHAP SEDSGKDRDS DEAVFLTA (514-660 aa encoded by BC130577)

Target Information

This gene encodes a member of the myotubularin family of tyrosine/dual-specificity phosphatases. The encoded protein is characterized by four distinct domains that are conserved among all members of the myotubularin family: the glucosyltransferase, Rab-like GTPase activator and myotubularins domain, the Rac-induced recruitment domain, the protein tyrosine phosphatases and dual-specificity phosphatases domain and the suppressor of variegation 3-9, enhancer-of-zeste, and trithorax interaction domain. This protein dephosphorylates the target substrates phosphatidylinositol 3-phosphate and inositol 1, 3-bisphosphate. A pseudogene of this gene is found on chromosome 5.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: DKFZp781E194; Inositol 1,3-bisphosphate phosphatase; MGC163449; MGC163451; Myotubularin-related protein 7; Phosphatidylinositol-3-phosphate phosphatase

Gene Aliases: MTMR7

UniProt ID: (Human) Q9Y216, (Mouse) Q9Z2C9

Entrez Gene ID: (Human) 9108, (Mouse) 54384, (Rat) 306490

Molecular Function: phosphatase

Function(s)
protein dephosphorylation phosphatidylinositol biosynthetic process peptidyl-tyrosine dephosphorylation inositol phosphate dephosphorylation phosphatidylinositol dephosphorylation dephosphorylation
Process(es)
phosphatidylinositol-3-phosphatase activity protein tyrosine phosphatase activity protein binding phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity protein tyrosine/serine/threonine phosphatase activity protein tyrosine/threonine phosphatase activity JUN kinase phosphatase activity phosphohistidine phosphatase activity inositol bisphosphate phosphatase activity hydrolase activity phosphatase activity MAP kinase tyrosine/serine/threonine phosphatase activity inositol-1,3,4-trisphosphate 4-phosphatase activity NADP phosphatase activity transmembrane receptor protein phosphatase activity inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity inositol-4,5-bisphosphate 5-phosphatase activity 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity phosphatidylinositol-4-phosphate phosphatase activity phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity inositol phosphate phosphatase activity inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity inositol-3,4-bisphosphate 4-phosphatase activity inositol-1,3,4-trisphosphate 1-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity IDP phosphatase activity

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