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Abnova
MTPN Polyclonal Antibody, MaxPab™
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FIGURE: 1 / 1
MTPN Antibody (H00136319-B01P) in WB
Western Blot analysis of MTPN expression in transfected 293T cell line (H00136319-T01) by MTPN MaxPab polyclonal antibody.
Lane1:MTPN transfected lysate(13.09 KDa).
Lane 2:Non-transfected lysate.
Lane1:MTPN transfected lysate(13.09 KDa).
Lane 2:Non-transfected lysate.
Product Details
H00136319-B01P
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MTPN (AAH28093, 1 a.a. approximately 118 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MCDKEFMWAL KNGGLDEVKD YVAKGEDVNR TLEGGRKPLH YAADCGQLEI LEFLLLKGAD INAPDKHHIT PLLSAVYEGH VSCVKLLLSK GADKTVKGPD GLTAFEATDN QAIKALLQ
Target Information
The transcript produced from this gene is bi-cistronic and can encode both myotrophin and leucine zipper protein 6. The myotrophin protein is associated with cardiac hypertrophy, where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers. This protein also has a potential function in cerebellar morphogenesis, and it may be involved in the differentiation of cerebellar neurons, particularly of granule cells. A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6, a 6. 4 kDa tumor antigen that is associated with myeloproliferative disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: granule cell differentiation protein; Myotrophin; Protein V-1
Gene Aliases: GCDP; MTPN; V-1
UniProt ID: (Human) P58546
Entrez Gene ID: (Human) 136319
regulation of translation
catecholamine metabolic process
positive regulation of macromolecule biosynthetic process
positive regulation of cardiac muscle hypertrophy
cell growth
regulation of striated muscle tissue development
cerebellar granule cell differentiation
neuron differentiation
positive regulation of cell growth
skeletal muscle tissue regeneration
positive regulation of NF-kappaB transcription factor activity
striated muscle cell differentiation
positive regulation of protein metabolic process
cellular response to mechanical stimulus
regulation of barbed-end actin filament capping
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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