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          • Primary Antibodies ›
          • MTR Antibodies

          Proteintech

          MTR Polyclonal Antibody

          9 References
          View all (7) MTR antibodies

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          Cite MTR Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (9)
          MTR Antibody in Immunocytochemistry (ICC/IF)
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          MTR Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 9

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          MTR Antibody (25896-1-AP) in ICC/IF

          Immunofluorescent analysis of A375 cells using 25896-1-AP (MTR antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MTR Antibody in Immunocytochemistry (ICC/IF)
          MTR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MTR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MTR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MTR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MTR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MTR Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          MTR Antibody in Western Blot (WB)
          MTR Antibody in Western Blot (WB)
          MTR Polyclonal Antibody

          Product Details

          25896-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:1,000
          View 7 publications 7 publications

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:20-1:200
          -

          Not applicable (N/A)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          MTR Fusion Protein Ag23156 (917-1265 aa encoded by BC130616)
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.3 mg/mL

          Amount

          45 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: RQGHYESLK ERRYLPLSQA RKSGFQMDWL SEPHPVKPTF IGTQVFEDYD LQKLVDYIDW KPFFDVWQLR GKYPNRGFPK IFNDKTVGGE ARKVYDDAHN MLNTLISQKK LRARGVVGFW PAQSIQDDIH LYAEAAVPQA AEPIATFYGL RQQAEKDSAS TEPYYCLSDF IAPLHSGIRD YLGLFAVACF GVEELSKAYE DDGDDYSSIM VKALGDRLAE AFAEELHERV RRELWAYCGS EQLDVADLRR LRYKGIRPAP GYPSQPDHTE KLTMWRLADI EQSTGIRLTE SLAMAPASAV SGLYFSNLKS KYFAVGKISK DQVEDYALRK NISVAEVEKW LGPILGYDTD (917-1265 aa encoded by BC130616)

          Target Information

          MTR encodes the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: 5-methyltetrahydrofolate--homocysteine methyltransferase; 5-methyltetrahydrofolate-homocysteine methyltransferase 1; Cobalamin-dependent methionine synthase; FLJ33168; FLJ43216; FLJ45386; Methionine synthase; MS; similar to Escherichia coli methionine synthase encoded by GenBank Accession Number J04975; unnamed protein product; Vitamin-B12 dependent methionine synthase

          View more View less

          Gene Aliases: AI894170; cblG; D830038K18Rik; HMAG; MS; MTR

          View more View less

          UniProt ID: (Human) Q99707, (Mouse) A6H5Y3

          View more View less

          Entrez Gene ID: (Human) 4548, (Mouse) 238505

          View more View less

          Function(s)
          protein binding methyltransferase activity zinc ion binding methionine synthase activity transferase activity cobalamin binding metal ion binding folic acid binding S-adenosylmethionine-homocysteine S-methyltransferase activity amino acid binding
          Process(es)
          sulfur amino acid metabolic process nervous system development cellular amino acid biosynthetic process methionine biosynthetic process cobalamin metabolic process axon regeneration methylation pteridine-containing compound metabolic process tetrahydrofolate metabolic process response to axon injury homocysteine metabolic process L-methionine salvage cellular response to nitric oxide protein methylation methionine metabolic process cellular metabolic process
          It has to be done as per old AB suggested Products section.

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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