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Immunogen sequence: TLDQVLEDVD QCCQALSQRL GTQPYFFNKQ PTELDALVFG HLYTILTTQL TNDELSEKVK NYSNLLAFCR RIEQHYFEDR G
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 94%.
The protein encoded by this gene is highly similar to the metaxin 2 protein from mouse, which has been shown to interact with the mitochondrial membrane protein metaxin 1. Because of this similarity, it is thought that the encoded protein is peripherally associated with the cytosolic face of the outer mitochondrial membrane, and that it is involved in the import of proteins into the mitochondrion. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 7.
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Protein Aliases: Metaxin-2; Metaxin2; Mitochondrial outer membrane import complex protein 2
Gene Aliases: MTX2
UniProt ID: (Human) O75431
Entrez Gene ID: (Human) 10651
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