Immunogen sequence: SGGRFRCPSC RHEVVLDRHG VYGLQRNLLV ENIIDIYKQE STRPEKKSDQ
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Predicted homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 86%; Zebrafish: 100%
The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein associates transiently with microtubules, myosin, and titin during muscle sarcomere assembly. It may act as a transient adaptor and plays a regulatory role in the assembly of sarcomeres. Four alternatively spliced transcript variants encoding distinct isoforms have been described.
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Protein Aliases: MuRF-2; muscle specific ring finger 2; Muscle-specific RING finger protein 2; RING finger protein 29; tripartite motif-containing 55; Tripartite motif-containing protein 55
Gene Aliases: MURF-2; MURF2; RNF29; TRIM55
UniProt ID: (Human) Q9BYV6
Entrez Gene ID: (Human) 84675
Molecular Function: ubiquitin-protein ligase