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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fusion protein containing a sequence corresponding to amino acids 179-358 of human TRIM54 |
Conjugate |
Unconjugated |
Form |
liquid |
Concentration |
2.35 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2805278 |
Immunogen sequence: AMLVAGNDRV QAVITQMEEV CQTIEDNSRR QKQLLNQRFE SLCAVLEERK GELLQALARE QEEKLQRVRG LIRQYGDHLE ASSKLVESAI QSMEEPQMAL YLQQAKELIN KVGAMSKVEL AGRPEPGYES MEQFTVRVEH VAEMLRTIDF QPGASGEEEE VAPDGEEGSA GPEEERPDGP; Positive Samples: A-549, Mouse heart; Cellular Location: Cytoplasm, Z line, cytoskeleton, myofibril, sarcomere
The protein encoded by this gene contains a RING finger motif and is highly similar to the ring finger proteins RNF28/MURF1 and RNF29/MURF2. In vitro studies demonstrated that this protein, RNF28, and RNF29 form heterodimers, which may be important for the regulation of titin kinase and microtubule-dependent signal pathways in striated muscles. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: MuRF; MuRF-3; Muscle-specific RING finger protein; Muscle-specific RING finger protein 3; muscle-specific RING-finger protein; muscle-specific RING-finger protein 3; OTTHUMP00000122598; RING finger protein 30; tripartite motif-containing 54; Tripartite motif-containing protein 54
Gene Aliases: 4930486E09Rik; 4930566I02Rik; MURF; MURF-3; MURF3; RNF30; TRIM54
UniProt ID: (Human) Q9BYV2, (Mouse) Q9ERP3
Entrez Gene ID: (Human) 57159, (Mouse) 58522
Molecular Function:
ubiquitin-protein ligase
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