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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MUS81 Antibodies

          Proteintech

          MUS81 Polyclonal Antibody

          3 References
          View all (6) MUS81 antibodies

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          Cite MUS81 Polyclonal Antibody

          • Antibody Testing Data (3)
          MUS81 Antibody in Immunocytochemistry (ICC/IF)
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          MUS81 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          MUS81 Antibody (11018-1-AP) in ICC/IF

          Immunofluorescent analysis of MCF-7 cells, using MUS81 antibody 11018-1-AP at 1:50 dilution and FITC-labeled donkey anti-rabbit IGG (green). Blue pseudocolor = DAPI (fluorescent DNA dye). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MUS81 Antibody in Immunocytochemistry (ICC/IF)
          MUS81 Antibody in Western Blot (WB)
          MUS81 Antibody in Western Blot (WB)
          MUS81 Polyclonal Antibody

          Product Details

          11018-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 2 publications 2 publications

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunocytochemistry (ICC/IF)

          1:20-1:200
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          MUS81 Fusion Protein Ag1476 (202-551 aa encoded by BC009999)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.17 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: RYSLTPEGL ELAQKLAESE GLSLLNVGIG PKEPPGEETA VPGAASAELA SEAGVQQQPL ELRPGEYRVL LCVDIGETRG GGHRPELLRE LQRLHVTHTV RKLHVGDFVW VAQETNPRDP ANPGELVLDH IVERKRLDDL CSSIIDGRFR EQKFRLKRCG LERRVYLVEE HGSVHNLSLP ESTLLQAVTN TQVIDGFFVK RTADIKESAA YLALLTRGLQ RLYQGHTLRS RPWGTPGNPE SGAMTSPNPL CSLLTFSDFN AGAIKNKAQS VREVFARQLM QVRGVSGEKA AALVDRYSTP ASLLAAYDAC ATPKEQETLL STIKCGRLQR NLGPALSRTL SQLYCSYGPL T (202-551 aa encoded by BC009999)

          Target Information

          Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Crossover junction endonuclease MUS81; FLJ21012; FLJ44872 MUS81; MUS81 endonuclease homolog; SLX3 structure-specific endonuclease subunit homolog

          View more View less

          Gene Aliases: 1200008A18Rik; AI182501; AW045863; MUS81; SLX3

          View more View less

          UniProt ID: (Human) Q96NY9, (Rat) Q4KM32, (Mouse) Q91ZJ0

          View more View less

          Entrez Gene ID: (Human) 80198, (Rat) 293678, (Mouse) 71711

          View more View less

          Function(s)
          DNA binding endodeoxyribonuclease activity protein binding crossover junction endodeoxyribonuclease activity metal ion binding 3'-flap endonuclease activity nuclease activity endonuclease activity hydrolase activity
          Process(es)
          DNA catabolic process, endonucleolytic DNA repair DNA recombination interstrand cross-link repair response to intra-S DNA damage checkpoint signaling DNA metabolic process cellular response to DNA damage stimulus
          It has to be done as per old AB suggested Products section.
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