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MUTED Antibody (PA5-23648) in IHC (P)
Immunohistochemistry analysis of MUTED in formalin fixed and paraffin embedded human tonsil tissue. Samples were incubated with MUTED polyclonal antibody (Product # PA5-23648) followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of this antibody for immunohistochemistry. Clinical relevance has not been evaluated.
Product Details
PA5-23648
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 40-68 amino acids from the central region of human MUTED
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2541148
Product Specific Information
This antibody is predicted to react with porcine based on sequence homology.
Target Information
This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: biogenesis of lysosomal organelles complex-1, subunit 5, muted; Biogenesis of lysosome-related organelles complex 1 subunit 5; biogenesis of organelles complex-1, subunit 5, muted; BLOC-1 subunit 5; muted homolog; Protein Muted homolog
Gene Aliases: 1810074A19Rik; BLOC1S5; BLOS5; MU; MUTED
UniProt ID: (Human) Q8TDH9, (Mouse) Q8R015
Entrez Gene ID: (Human) 63915, (Mouse) 17828
anterograde axonal transport
neuron projection development
melanosome transport
melanosome organization
endosome to melanosome transport
anterograde synaptic vesicle transport
positive regulation of pigment cell differentiation
vesicle-mediated transport
otolith morphogenesis
developmental pigmentation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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