FIGURE: 1 / 2
Immunogen sequence: ISCTVEGAPA SFGKSFAQKS GYFLCLSSLG SLENPQENVV ADIQIVVDKS PLPLGFSPVC DPMDSKASVS KKKRMCVKLL PL
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 74%.
FAM125A, also named as MVB12A and CFBP, is a component of the ESCRT-I complex. FAM125A is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. FAM125A has three isoforms with MW 27-28 kDa and 25 kDa.
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Protein Aliases: CIN85/CD2AP family binding protein; CIN85/CD2AP family-binding protein; ESCRT-I complex subunit MVB12A; family with sequence similarity 125, member A; Multivesicular body subunit 12A; Protein FAM125A
Gene Aliases: CFBP; FAM125A; MVB12A
UniProt ID: (Human) Q96EY5
Entrez Gene ID: (Human) 93343