This antibody can recognize the endogenous Mx1 protein in several tissues like lung and spleen.
This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: IFI-78K; Influenza resistance protein; Interferon-induced GTP-binding protein Mx1; Interferon-induced GTP-binding protein Mx1, N-terminally processed; Interferon-induced protein p78; interferon-inducible protein p78; Interferon-regulated resistance GTP-binding protein MxA; MX dynamin-like GTPase 1; Myxoma resistance protein 1; myxovirus (influenza virus) resistance 1; myxovirus (influenza virus) resistance 1, interferon-inducible protein p78; myxovirus (influenza) resistance 1 polypeptide; Myxovirus resistance protein 1
Gene Aliases: AI893580; IFI-78K; IFI78; MX; Mx-1; MX1; MxA
Molecular Function: membrane traffic protein