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Proteintech
MX2 Polyclonal Antibody
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Product Details
13278-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MX2 fusion protein Ag4020
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: RLAERLTTEL IMHIQKSLPL LEGQIRESHQ KATEELRRCG ADIPSQEADK MFFLIEKIKM FNQDIEKLVE GEEVVRENET RLYNKIREDF KNWVGILATN TQKVKNIIHE EVEKYEKQYR GKELLGFVNY KTFEIIVHQY IQQLVEPALS MLQKAMEIIQ QAFINVAKKH FGEFFNLNQT VQSTIEDIKV KHTAKAENMI QLQFRMEQMV FCQDQIYSVV LKKVREEIFN PLGTPSQNMK LNSHFPSNES SVSSFTEIGI HLNAYFLETS KRLANQIPFI IQYFMLRENG DSLQKAMMQI LQEKNRYSWL LQEQSETATK RRILKERIYR LTQARHALCQ FSSKEIH
Target Information
Members of the Dynamin family include GTPase, microtubule-associated proteins that are involved in cellular trafficking, including microtubule bundling and endocytosis. Mx1, also known as MxA, an interferon (IFN)-induced protein, acquires a high degree of resistance to influenza A virus and the rhabdo-virus vesicular stomatitis virus (VSV), which suggests that Mx1 plays an active role against influenza virus and the rhabdovirus VSV. Mx1 is a cytoplasmic protein that is 63% identical to the Mx2 protein, which lacks antiviral activity. Mx2 is also known as MxB and is localized at the cytoplasmic face of nuclear pores. Mx2 expression is not interferon-dependent and this protein is thought to regulate the efficiency and/or kinetics of nuclear import, a function which may have been usurped by its antiviral relatives.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; MX dynamin-like GTPase 2; myxovirus (influenza virus) resistance 2; Myxovirus resistance protein 2; p78-related protein; protein MxB; second interferon-induced protein p78
Gene Aliases: MX2; MXB
UniProt ID: (Human) P20592
Entrez Gene ID: (Human) 4600
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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