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Invitrogen
MXD1 Polyclonal Antibody
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Product Details
PA5-100285
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MXD1(Accession Q05195), corresponding to amino acid residues D158-R208.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total MXD1.
Target Information
MAX dimerization protein belongs to a subfamily of MAX-interacting proteins. This protein competes with MYC for binding to MAX to form a sequence-specific DNA-binding complex, acts as a transcriptional repressor (while MYC appears to function as an activator) and is a candidate tumor suppressor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: antagonizer of myc transcriptional activity; Max dimerization protein 1; Max dimerizer 1; MAX-binding protein; MGC104659; OTTHUMP00000202211; Protein MAD
Gene Aliases: AW122478; BHLHC58; MAD; Mad-1; MAD1; MXD1
UniProt ID: (Human) Q05195
Entrez Gene ID: (Human) 4084, (Rat) 362391, (Mouse) 17119
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription cofactor activity
transcription corepressor activity
protein binding
protein dimerization activity
DNA binding
basic helix-loop-helix transcription factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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