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|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide corresponding to residues in human MXRA5|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7.2|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects endogenous protein at a molecular weight of 312 kDa.
Purity is >95% by SDS-PAGE.
Matrix-remodeling-associated protein 5 (MXRA5), also known as adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan (Adlican), is a 2,828 amino acid secretory protein. Containing 12 Ig-like C2-type domains and 7 LRR repeats, MXRA5 is a member of the leucine-rich repeat and Ig domain-containing (LRRIG) family of proteins. MXRA5 expression, while decreasing with age from youth until late adulthood, increases from late adulthood through late elderhood. Most notably, NXRA5 has been shown to be overexpressed in centenarians. This expression pattern suggests a role of MXRA5 in the biology of aging and longevity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan; Adlican; Matrix-remodeling-associated protein 5; matrix-remodelling associated 5