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MYADM Polyclonal Antibody
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FIGURE: 1 / 1
MYADM Antibody (BS-19143R) in WB
Lane 1: A549 cell lysates; Lane 2: Hela cell lysates; Lane 3: Panc-1 cell lysates probed with MYADM Polyclonal Antibody, Unconjugated (bs-19143R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.
Product Details
BS-19143R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human MYADM, amino acids 51-150.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.03% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
MYADM, belonging to the MAL family, is a 322-amino acid protein having 7 hydrophobic transmembrane domains, several potential consensus sites for phosphorylation and sequence homology with the T-cell differentiation protein MAL and plasmolipin. It shares 75.8% sequence identity with mouse in the transmembrane regions and is associated with differentiation of hematopoietic cells or acute promyelocytic leukemia cells. Its expression is up-regulated in NB4 cells induced by all-trans retinoic acid whereas down regulation inhibits colony formation of bone marrow cells. MYADM could serve as a new marker for hematopoietic differentiation and is a target for diagnostic, prognostic and/or therapeutic interventions. It is known to express widely in brain and pancreatic islet cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: muG; myeloid upregulated protein; Myeloid-associated differentiation marker; Protein SB135; unnamed protein product
Gene Aliases: MYADM; SB135; UNQ553/PRO1110
UniProt ID: (Human) Q96S97
Entrez Gene ID: (Human) 91663
negative regulation of gene expression
regulation of cell-substrate adhesion
positive regulation of cell migration
negative regulation of actin filament polymerization
membrane raft organization
negative regulation of heterotypic cell-cell adhesion
intracellular signal transduction
protein localization to plasma membrane raft
cell-cell junction maintenance
establishment of endothelial barrier
positive regulation of substrate adhesion-dependent cell spreading
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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