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Invitrogen
MYBPC1 Polyclonal Antibody
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FIGURE: 1 / 2
MYBPC1 Antibody (PA5-101687) in ICC/IF
Immunofluorescent analysis of MYBPC1 in HeLa cells. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C), incubated with mouse anti-beta tubulin and MYBPC1 polyclonal antibody (Product # PA5-101687) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 (red) and goat anti-mouse IgG Alexa Fluor 488 (green).
Product Details
PA5-101687
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MYBPC1(Accession Q00872), corresponding to amino acid residues A217-G267.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total MYBPC1.
Target Information
Myosin binding protein C (MYBPC) is a component of the thick filament of striated muscle, with the slow-type isoform designated MYBPC1. Both the fast-type (MYBPC2) and slow-type MYBPC protein contains seven immunoglobulin C2 motifs and three fibronectin type-III repeats. Multiple isoforms of MYBPC1 are known to exist, and are present in varying amounts in different skeletal muscles. It is thought that the MYBPC1 slow subfamily may play important roles in the assembly and stabilization of sarcomeric M- and A-bands and regulate the contractile properties of the actomyosin filaments.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: C-protein, skeletal muscle slow isoform; muscle C-protein; MyBP-C slow; myosin binding protein C, slow type; Myosin-binding protein C, slow-type; skeletal muscle C-protein; Slow MyBP-C; slow skeletal-type muscle myosin-binding-protein C; Slow-type C-protein; unnamed protein product
Gene Aliases: 8030451F13Rik; CMYO16; CMYP16; LCCS4; MYBPC1; MYBPCC; MYBPCS; MYOTREM; ssMyBP-C
UniProt ID: (Human) Q00872, (Rat) Q63518
Entrez Gene ID: (Human) 4604, (Mouse) 109272, (Rat) 362867
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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